Jennifer Yu, MD, PhD

Cleveland Clinic Taussig Cancer Institute, Cleveland Clinic Lerner Research Institute


Pilot Grant

Wnt Signaling in Glioblastoma

Glioblastoma is an incurable primary brain tumor. The Wnt pathway is frequently dysregulated in many cancers, including glioblastoma, underscoring it as an important therapeutic target. This work will reveal a novel mechanism by which Wnt signaling is activated independent of Wnt ligand-receptor binding. If successful, the findings of this study will provide new strategies to improve treatment for glioblastoma.

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